Pseudallescheria boydii has long been known to cause white grain mycetoma in immunocompetent humans, but it has recently emerged as an. Scedosporium apiospermum, an anamorph of pseudallescheria boydii, is a hyalohyphomycete which can be mistaken, histologically, for aspergillus. Pseudallescheria boydii and its asexual anamorph, scedosporium, are ubiquitous filamentous fungi found in soil, water, and sewage 1. Typically found in stagnant and polluted water, it has been implicated in the infection of immunocompromised and neardrowned pneumonia patients. Scedosporiumpseudallescheria infections request pdf. Scedosporium apiospermum is a ubiquitous saprophytic fungus commonly found in soil, manure, decaying vegetation, and polluted water. Molecular phylogeny of the pseudallescheria boydii species. Speciesspecific antifungal susceptibility patterns of scedosporium. Scedosporium apiospermum, pseudallescheria boydii, central nervous system infections, brain abscess, cerebral infections, fungal meningitis. V alikhani from the department of medical mycology, school of public health and institute of public health research and department of dermatology, razi hospital, tehran university of medical sciences, tehran, islamic republic of iran. Pdf on jun 30, 2019, yongwoo choi and others published macroscopic and microscopic findings of pseudallescheria boydii find, read and cite all the.
Pseudallescheria apiosperma was detected in 20 samples, while pseudallescheria boydii and pseudallescheria aurantiacum were detected in 17 and eight samples, respectively. Pdf macroscopic and microscopic findings of pseudallescheria. Its commonest clinical presentation in the usa is as mycetoma, a chronic limited subcutaneous infection in immunocompetent individuals engendered by minor trauma, and is characterised by grain. Discussion p boydii has been increasingly recognized as a pathogen in immunocompromised hosts. Since the separation of pseudallescheria boydii and p. Orbital apex syndrome secondary to a sphenoidal sinus mycetoma of pseudallescheria boydii has also been reported. Pseudallescheria boydii infection after bone marrow.
Case presentation a 10yearold white male was struck beneath the right eye by a. Pseudallescheria boydii petriellidium boydii infection. Tracking the emerging human pathogen pseudallescheria. Pseudallescheria species and their anamorphs in the genus scedosporium classically are known.
Pseudallescheria boydii is not a common agent of mycotic keratitis. D department of medicine, lsu medical school, 1542 tulane avenue. In the course of the past decades, pseudallescheriascedosporium. Pseudallescheria boydii, petriellidium boydii, can now be added to the list of recognized orbital pathogens. Identification of pseudallescheria and scedosporium species by. Although pseudallescheria boydii is the most common cause of mycetoma in the united states, 172174 pulmonary infection is rare. Pseudallescheria boydii anamorph scedosporium apiospermum infection in solid organ transplant recipients in a tertiary medical center. Pseudallescheria boydii pneumonia in an immunocompetent host. Invasive infection caused by pseudallescheria boydii in an. Pseudallescheria boydii westerdijk fungal biodiversity institute.
What links here related changes upload file special pages permanent link page. Pdf the study compared the growth of pseudallescheria boydii isolates from sewage sludge and from clinical sources on tributyrin, rapeseed oil. Requests for reprints should be addressed to conrad h. Disseminated pseudallescheria boydii infection in a. Pseudallescheria boydii an overview sciencedirect topics. Isolation and clinical significance of pseudallescheria and. Disseminated disease and pulmonary, sinus, bone, cns, and kidney infections have been described in hosts with a variety of underlying conditions, including hematologic malignancies, diabetes. Pseudallescheria boydii has long been known to cause white grain mycetoma in immunocompetent humans, but it has recently emerged as an opportunistic pathogen of humans, causing potentially fatal invasive infections in immunocompromised individuals and evacuees of natural disasters, such as tsunamis and hurricanes.
Pseudallescheria boydii is a species of fungus classified in the ascomycota. Pseudallescheria boydii anamorph scedosporium apiospermum is the. Tracking the emerging human pathogen pseudallescheria boydii. Pseudallescheria boydii is a saprophytic fungus frequently isolated from agricultural and industrial soil and from polluted water 1. It is associated with some forms of eumycetoma, maduromycosis and pseudallescheriasis.